Self drive at your own pace. Explore the attractions of Cape Town like Table
Africa is home to some of the world’s most spectacular wildlife destinations and breathtaking natural wonders. Although the continent is generally safer and easier to explore than many travelers expect, there is one health consideration that may influence your choice of location: malaria.
Malaria is transmitted through the bite of an infected female Anopheles mosquito, and it remains a concern in many tropical and subtropical regions of Africa, particularly during and shortly after the rainy season.
The positive news is that several of our top safari and beach destinations carry a very low risk of malaria — a risk that becomes even lower in the dry months. Even better, we offer carefully selected malaria-free safari regions where you can enjoy classic big-game viewing or unwind on idyllic beaches without worry. These areas are ideal for family safaris, especially when traveling with children, and for guests such as pregnant women or anyone who wishes to avoid the inconvenience or potential side effects of anti-malaria medication.
South Africa’s malaria-free safari regions are ideally positioned to pair seamlessly with some of Africa’s finest beach and island destinations. The following locations are not only malaria-free but also easy to combine with the wildlife areas mentioned above:
Mauritius offers exceptional diversity, delivering memorable holidays for families, golfers, honeymooners, adventure lovers, and scuba enthusiasts. Its blend of culture, scenery, and world-class resorts makes it a perfect complement to your safari journey.
Renowned as one of the world’s most indulgent island getaways, the Seychelles focuses on exclusive, high-end beach experiences. It’s an ideal choice for honeymooners and sophisticated travelers seeking genuine barefoot, five-star luxury.
A trip to South Africa isn’t complete without experiencing Cape Town. With its Blue Flag beaches, lush landscapes, scenic vineyards, and iconic mountain ranges, it’s often regarded as one of the most beautiful cities in the world. Spend time in the vibrant “Mother City” before or after your malaria-free safari and enjoy top attractions, gourmet cuisine, fine wines, and boutique shopping.
A beloved option for families, the Garden Route offers dramatic scenery, long stretches of coastline, and charming towns along the way. This self-drive paradise promises peaceful beaches, whale watching (June to October), picturesque hiking trails, and laid-back coastal stops perfect for every type of traveler.
While more than 90% of South Africa lies outside malaria-risk areas, the disease is more common during the green season (November to April). Traveling in the dry season (May to October) dramatically lowers the chance of encountering mosquitoes, with little to no need for extra protection in low-risk and no-risk zones.
Even in low or no-risk regions, it’s best to stay at accommodations that take proper mosquito-control measures. Look for properties with insect screens, bed nets, or routine insecticide treatments to help reduce mosquito activity.
For added peace of mind, bring along natural mosquito repellent and lightweight long-sleeved clothing to wear in the evenings. These small precautions help ensure a completely worry-free experience.
Working with an expert who understands malaria-free destinations makes planning your safari far easier. A knowledgeable specialist can recommend the best regions, lodges, and activities suited to your interests. They also handle visa advice, flight arrangements, and on-ground support — giving you confidence and comfort throughout your journey.
From £11,745 to £11,790 pps



Self drive at your own pace. Explore the attractions of Cape Town like Table
Cape Town, Cape Winelands, Franschhoek, South Africa, Whale Coast
From £15,675 to £21,150 pps



Full-day family fun tour in Franschhoek. Explore Cape Town & the scenic Winelands.
Cape Town, Cape Winelands, Eastern Cape, South Africa
From £3,395 to £3,915 pps



Stay in the cosmopolitan heart of Cape Town. Explore Cape Town’s beaches & vineyards.
Cape Town, Cape Winelands, Garden Route, South Africa, Whale Coast
From £8,615 to £10,865 pps



Explore a private reserve in the malaria-free Marakele National Park. Delight in the food,
Cape Winelands, Eastern Cape, Franschhoek, South Africa
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